Origin Diagnostics Drug Testing

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Be aware that certain foods and over-the-counter medications can cause you to test “positive” for various kinds of drugs.

Poppy seeds, for example, can show up on a drug test as morphine. Cold remedies that contain codeine can also cause a positive result for morphine.

Valium reportedly can produce erroneous indications of phencyclidine (PCP), and other cold remedies can apparently produce false reports of methamphetamine usage.

Dextromethorphan can produce a falsely positive qualitative urine opiate screening.

The widespread availability of hemp-containing products, including everything from hemp-seed oil nutritional supplements to hemp-seed candy, cookies, cheese, bread, cooking oil, and general seasoning, means that ingesting ANY of these products could potentially cause a false positive result on a test for marijuana.

Ibuprofen, contained in Advil, Nuprin, and Mortin, can make a positive result for marijauna. The EMIT test (an immunoassay test) has therefore been changed to use a different enzyme to eliminate false positives due to Ibuprofen. Ibuprofen in very high doses will still interfere with both the EMIT and the gas chromatograph-mass spectrometer (GC-MS) test.

Ibuprofen is a common pain reliever that (even in low dosages) used to cause a false THC positive on the EMIT test. The EMIT has been changed to use a different enzyme to eliminate false positives due to Ibuprofen. Ibuprofen in very high doses will still interfere with both the EMIT and the GC-MS. There is some conflicting data here because some sources say that the GC-MS tests can distinguish between Ibuprofen and THC (as well as other over-the-counter drugs).

Common over the counter cold, asthma, and allergy remedies and diet pills such as Diatec, Dexatrim, Cotylenol, Triaminic, Primatene, Bronkotabs, and Nyquil can show up as positive for amphetamines.

Vicks Formula-44, Demerol, Mydol, Primatene-M and common prescription antidepressants such as Elavil and Tofanil can show up as positive for opiates such as opium and heroin.

Ephedra, also known as Ephedra Alkaloids or “MaHuang Extract” has a chemical structure which is closely related to amphetamine, and can reportedly give a false positive for amphetamines. Often sold as an “energy pill” it is an effective decongestant in low doses.

Valerian root is reported to cause false positives for benzodiazepines. Other herbal supplements such as Kava Kava and St Johns Wort may also affect body chemistry such that false positives are produced.

Zoloft (Wellbutrin) is reported to cause false positives in urine screens, although for what specific substance isn’t clear.

Primatene can also show up as positive for barbiturates, and Benadryl can show up positive for Methadone.

Some additional over the counter medicines that may cause various kinds of drug test interactions include Alka-Seltzer plus, Allerest, Bronkaid, Contac, Donnagel, Sinuntab, and Sudafed.

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The basic drug test used by most corporate drug testing programs is called a Five-Screen (or NIDA-5 or SAMHSA-5) which is testing for five types of drugs:

1. Cannabinoids (Marijuana, Hashish)
2. Cocaine (Cocaine, Crack, Benzoylecognine)
3. Opiates (Heroin, Opium, Codeine, Morphine
4. Amphetamines (Methamphetamines, Speed)
5. Phencyclidine (PCP, Angel Dust)

However, many drug testing firms now offer a Ten-Screen which expands to include five additional drugs:

1. Barbituates (Phenobarbital, Secobarbitol, Pentobarbital, Butalbital, Amobarbital)
2. Methaqualone (Qualuudes)
3. Benzodiazepines (Tranquilizers-Diazepam, Valium, Librium, Ativan, Xanax, Clonopin, Serax, Halcion, Rohypnol)
4. Methadone
5. Propoxyphene (Darvon compounds)

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According to a news report from the Los Angeles Times New Service, a study of 161 prescription and over the counter medications showed that 65 of them produced false positive drug test results in the most widely administered urine drug test procedure. Ronald Siegel, a psychopharmacologist at UCLA said ‘The widespread testing and reliance on tell-tale traces of drugs in the urine is simply a panic reaction invoked because the normal techniques for controlling drug use haven’t worked very well. The next epidemic will be testing abuse.” Currently there are more than 250 over-the-counter medications and prescription drugs that can cause false positives.  

Click on links to find false positive drugs:

Marijuana (THC)
Tricyclic Antidepressants (TCA)
Barbiturates (BAR)
Buprenorphine (BUP)
Benzodiazepines (BZO)
Phencyclidine (PCP)
Methadone (MTD)
Oxycodone (OXY)
Methamphetamine (MAMP)
Amphetamines (AMP)
Propoxyphene (PPX)
Opiates and Morphine (OPI or MOR)

Note: Cocaine (COC) and Ecstasy (MDMA) has no cross reaction drugs at this time.

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Synonyms for Barbiturates in General: Sleeping Pills

Street Names for Barbiturates: Barbs, Downers

Barbiturates are commonly divided into groups based on the onset and duration of their action. The intermediate and short-acting barbiturates are the categories most commonly abused, most notably Seconal (secobarbital) and Tuinal (secobarbital with amobarbital). Long-acting barbiturates have an onset of action of 30 to 60 minutes and a duration of action of 6 to 8 hours.

Examples of long-acting barbiturates are phenobarbital and barbital. Their slow onset of action discourages their abuse.
The intermediate-acting barbiturates have an onset of action of 15 to 30 minutes and a duration of action of 4 to 6 hours.

Examples of intermediate-acting barbiturates are amobarbital, butabarbital, and Tuinal.
The short-acting barbiturates have an onset of action of 10 to 15 minutes and have a duration of action of 2 to 4 hours.

Examples of short-acting barbiturates are secobarbital and pentobarbital.
The ultra-short-acting barbiturates have an onset of action of 0 to 45 seconds and a duration of action 15 minutes to 3 hours. These are barbiturates used as anesthetics. Their effects are generally felt within one minute of intravenous administration.

Examples of ultra short-acting barbiturates are thiopenthal sodium, hexobarbital, and methohexital. The rapid onset and brief duration of action practically precludes the use of ultra-short-acting barbiturates in the street environment.
Concern about the addiction potential of barbiturates and the ever-increasing numbers of fatalities associated with them led to the development of alternative medications.

Barbiturates can be detected in urine drug testing from 2 to 10 days. Depending on usage.

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Certain over the counter medications can interfere with accurate results. These include ibuprofen and ephedrine-based products. Most drug testing companies will ask the applicant in advance what medications they have recently taken. The applicant should list these carefully. If the medication has compromised the result of the drug test the sample is automatically retested using a methodology that will identify the drug type. The applicant can present a doctor’s prescription for the medication that can be reviewed by the medical officer. Some medications will preliminarily test non-negative, but the confirmatory tests will rule out any non-illegal substances

Employers cannot discriminate in their hiring practices based on an applicant’s use of prescription medication for legitimate medical purposes. Such discrimination could be a violation of the Americans with Disabilities Act. Click on the link for:

Cross Reaction Drug Chart

Note: Cocaine (COC) and Ecstasy (MDMA) has no cross reaction drugs at this time.