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Medicine and Food That Interact With Drug Tests

10:01 am in Employee Drug Testing Information by admin

http://www.origindiagnostics.com

Be aware that certain foods and over-the-counter medications can cause you to test “positive” for various kinds of drugs.

Poppy seeds, for example, can show up on a drug test as morphine. Cold remedies that contain codeine can also cause a positive result for morphine.

Valium reportedly can produce erroneous indications of phencyclidine (PCP), and other cold remedies can apparently produce false reports of methamphetamine usage.

Dextromethorphan can produce a falsely positive qualitative urine opiate screening.

The widespread availability of hemp-containing products, including everything from hemp-seed oil nutritional supplements to hemp-seed candy, cookies, cheese, bread, cooking oil, and general seasoning, means that ingesting ANY of these products could potentially cause a false positive result on a test for marijuana.

Ibuprofen, contained in Advil, Nuprin, and Mortin, can make a positive result for marijauna. The EMIT test (an immunoassay test) has therefore been changed to use a different enzyme to eliminate false positives due to Ibuprofen. Ibuprofen in very high doses will still interfere with both the EMIT and the gas chromatograph-mass spectrometer (GC-MS) test.

Ibuprofen is a common pain reliever that (even in low dosages) used to cause a false THC positive on the EMIT test. The EMIT has been changed to use a different enzyme to eliminate false positives due to Ibuprofen. Ibuprofen in very high doses will still interfere with both the EMIT and the GC-MS. There is some conflicting data here because some sources say that the GC-MS tests can distinguish between Ibuprofen and THC (as well as other over-the-counter drugs).

Common over the counter cold, asthma, and allergy remedies and diet pills such as Diatec, Dexatrim, Cotylenol, Triaminic, Primatene, Bronkotabs, and Nyquil can show up as positive for amphetamines.

Vicks Formula-44, Demerol, Mydol, Primatene-M and common prescription antidepressants such as Elavil and Tofanil can show up as positive for opiates such as opium and heroin.

Ephedra, also known as Ephedra Alkaloids or “MaHuang Extract” has a chemical structure which is closely related to amphetamine, and can reportedly give a false positive for amphetamines. Often sold as an “energy pill” it is an effective decongestant in low doses.

Valerian root is reported to cause false positives for benzodiazepines. Other herbal supplements such as Kava Kava and St Johns Wort may also affect body chemistry such that false positives are produced.

Zoloft (Wellbutrin) is reported to cause false positives in urine screens, although for what specific substance isn’t clear.

Primatene can also show up as positive for barbiturates, and Benadryl can show up positive for Methadone.

Some additional over the counter medicines that may cause various kinds of drug test interactions include Alka-Seltzer plus, Allerest, Bronkaid, Contac, Donnagel, Sinuntab, and Sudafed.

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False Positive Drug Tests

5:49 pm in Employee Drug Testing Information by admin

http://www.origindiagnostics.com

According to a news report from the Los Angeles Times New Service, a study of 161 prescription and over the counter medications showed that 65 of them produced false positive drug test results in the most widely administered urine drug test procedure. Ronald Siegel, a psychopharmacologist at UCLA said ‘The widespread testing and reliance on tell-tale traces of drugs in the urine is simply a panic reaction invoked because the normal techniques for controlling drug use haven’t worked very well. The next epidemic will be testing abuse.” Currently there are more than 250 over-the-counter medications and prescription drugs that can cause false positives.  

Click on links to find false positive drugs:

Marijuana (THC)
Tricyclic Antidepressants (TCA)
Barbiturates (BAR)
Buprenorphine (BUP)
Benzodiazepines (BZO)
Phencyclidine (PCP)
Methadone (MTD)
Oxycodone (OXY)
Methamphetamine (MAMP)
Amphetamines (AMP)
Propoxyphene (PPX)
Opiates and Morphine (OPI or MOR)

Note: Cocaine (COC) and Ecstasy (MDMA) has no cross reaction drugs at this time.

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What’s Buprenorphine?

10:10 pm in Employee Drug Testing Information by admin

http://www.origindiagnostics.com

Buprenorphine is an opioid partial agonist. This means that, although buprenorphine is an opioid, and thus can produce typical opioid agonist effects and side effects such as euphoria and respiratory depression, its maximal effects are less than those of full agonists like heroin and methadone. At low doses buprenorphine produces sufficient agonist effect to enable opioid-addicted individuals to discontinue the misuse of opioids without experiencing withdrawal symptoms. The agonist effects of buprenorphine increase linearly with increasing doses of the drug until at moderate doses they reach a plateau and no longer continue to increase with further increases in dose—the “ceiling effect.” Thus, buprenorphine carries a lower risk of abuse, addiction, and side effects compared to full opioid agonists. In fact, in high doses and under certain circumstances, buprenorphine can actually block the effects of full opioid agonists and can precipitate withdrawal symptoms if administered to an opioid-addicted individual while a full agonist is in the bloodstream.

Buprenorphine has poor oral bioavailability and moderate sublingual bioavailability. Formulations for opioid addiction treatment are in the form of sublingual tablets.

Buprenorphine is highly bound to plasma proteins. It is metabolized by the liver via the cytochrome P4503A4 enzyme system into norbuprenorphine and other metabolites. The half-life of buprenorphine is 24–60 hours.

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What is Heroin?

3:41 pm in Employee Drug Testing Information by admin

http://www.origindiagnostics.com

Heroin is an illegal, highly addictive, opiate drug. Its abuse is more widespread than any other opiate. Heroin is processed from morphine, a naturally occurring substance extracted from the seed pod of certain varieties of poppy plants. It is typically sold as a white or brownish powder, or as the black sticky substance known on the streets as “black tar heroin.” Although purer heroin is becoming more common, most street heroin is “cut” with other drugs or with substances such as sugar, starch, powdered milk, or quinine.

Heroin is a semi-synthetic opiate derived from morphine or codeine and is the most potent of the opiates. It is typically found in white to brown powdered form and is injected, sniffed, or smoked. In the past, powders sold as illicit heroin typically contained only 1% to 10% of the drug.

Slang terms: “smack”, “junk”, “horse”, “skag”, “H”, “China white”

Indicated for:

Relief of extreme pain
Recreational uses:

Euphoria
Relaxation
Other uses:

Pain relief
Cough suppressant
Anti-diarrhea