Origin Diagnostics Drug Testing

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According to a news report from the Los Angeles Times New Service, a study of 161 prescription and over the counter medications showed that 65 of them produced false positive drug test results in the most widely administered urine drug test procedure. Ronald Siegel, a psychopharmacologist at UCLA said ‘The widespread testing and reliance on tell-tale traces of drugs in the urine is simply a panic reaction invoked because the normal techniques for controlling drug use haven’t worked very well. The next epidemic will be testing abuse.” Currently there are more than 250 over-the-counter medications and prescription drugs that can cause false positives.  

Click on links to find false positive drugs:

Marijuana (THC)
Tricyclic Antidepressants (TCA)
Barbiturates (BAR)
Buprenorphine (BUP)
Benzodiazepines (BZO)
Phencyclidine (PCP)
Methadone (MTD)
Oxycodone (OXY)
Methamphetamine (MAMP)
Amphetamines (AMP)
Propoxyphene (PPX)
Opiates and Morphine (OPI or MOR)

Note: Cocaine (COC) and Ecstasy (MDMA) has no cross reaction drugs at this time.

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Knowing how easy it is to tamper with urine samples and alter test results. The first objective is to find out if the urine sample is legitimate.

Color: If a urine sample looks clear, one can suspect that it’s watered down and may reject the sample and inform the employer about an adulteration attempt.

Temperature: Urine should be between 91 and 97 degrees. NIDA certified labs will verify temperature. If it isn’t, it is a possibility that water has been added to the cup or a substitution has been added.

Creatinine: Creatinine is a substance produced by vertebrates, and it shows up in urine. If someone substitutes their urine with something other than urine, like Mountain Dew, they will test negative for drugs. The tester will most likely not get away with it because Mountain Dew contains zero Creatinine, and an adulterant test detects Creatinine levels to ensure that the sample is valid. Creatinine levels drop below normal when people dilute their urine. This tests to ensure that the subject didn’t drink unusual amounts of water.

pH: pH is often changed when people spike their sample with household products.

Specific gravity: An unusual specific gravity indicates that a sample has been tampered with.

Age: Age can not be tested using urine. There is a rumor that approximate age can be detected in urine, and is tested in medical insurance exams. It’s a myth. Gender: Gender cannot be tested either. As with age, there is a rumor that gender can be detected in urine, and is tested in medical insurance exams. It’s another myth. It may be argued that a pregnancy test can be used to detect the gender of the urine provider, but the same test is used to detect prostate cancer in males.

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Street Names: Downers, Nerve Pills, Tranks

Description: The benzodiazepines are central nervous system (CNS) depressants commonly prescribed for the short-term treatment of anxiety and insomnia. Chlordiazepoxide (Librium) was the first benzodiazepine produced. Diazepam (Valium) was the next to be developed and until the early 1980′s this was the most widely prescribed tranquillizer in the world. Today, newer benzodiazepines such as alprazolam (Xanax) and lorazepam (Ativan) account for most tranquillizer prescriptions.
Benzodiazepines can be detected in urine drug screening from 10 days to 10 weeks depending on usage.

The widespread availability of benzodiazepines has made them common as drugs of abuse. Long-term users typically develop a tolerance to the drugs, requiring larger doses to achieve the desired effects. A psychological and/or physical dependence can develop, making it difficult to discontinue use. Some drug abusers take benzodiazepines to bring them down after using stimulants such as ecstasy or cocaine. Others take them to enhance the effects of alcohol. They are also commonly used as replacement drugs when a user’s drug of first choice is not available.

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MDMA or ecstasy is a Schedule I, synthetic, psychoactive drug possessing stimulant and hallucinogenic properties. Ecstasy possesses chemical variations of the stimulant amphetamine or methamphetamine and a hallucinogen, most often mescaline. Ecstasy is a semi-synthetic chemical compound.

MDMA use is closely tied to the underground rave (and dance club) scene throughout the world, but has also been widely used by therapists as an adjunct to psychotherapy. Because MDMA is so popular and because it goes well with dance parties, the demand for it usually exceeds supply–especially at any given location on any given night.

MDMA, or ‘ecstasy’ is a ‘psychedelic amphetamine’ that has gained popularity over the past 20 years because of its ability to produce strong feelings of comfort, empathy, and connection to others. It most frequently comes in tablet form, although it is occasionally sold in capsules or as powder. It is most frequently used orally and rarely snorted.

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Marijuana is a green or gray mixture of dried, shredded flowers and leaves of the hemp plant (Cannabis sativa). It is the most often used illegal drug in this country. All forms of cannabis are mind-altering (psychoactive) drugs that contain THC (delta-9-tetrahydrocannabinol), the main active chemical in marijuana.

THC is the chemical in marijuana which makes you feel “high” (which means experiencing a change in mood and seeing or feeling things differently). Certain parts of the plant contain higher levels of THC. The flowers or “buds” have more THC than the stems or leaves.

When  marijuana is smoked, THC goes quickly into the blood through the lungs and then to the brain (this is when the “high” is felt and can happen within a few minutes and can last up to five hours). THC is absorbed more slowly into the blood when marijuana is eaten because it has to pass through the stomach and intestine and can take up to one hour to experience the “high” effects, which can last up to 12 hours. THC is absorbed quickly into body fat and is then released very slowly back into the blood. This process can take up to one month for a single dose of THC to fully leave the body.

Marijuana, the most often used illegal drug in this country, is a product of the hemp plant, Cannabis sativa. The main active chemical in marijuana, also present in other forms of cannabis, is THC (delta-9-tetrahydrocannabinol). Of the roughly 400 chemicals found in the cannabis plant, THC affects the brain the most.

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Synonyms for Barbiturates in General: Sleeping Pills

Street Names for Barbiturates: Barbs, Downers

Barbiturates are commonly divided into groups based on the onset and duration of their action. The intermediate and short-acting barbiturates are the categories most commonly abused, most notably Seconal (secobarbital) and Tuinal (secobarbital with amobarbital). Long-acting barbiturates have an onset of action of 30 to 60 minutes and a duration of action of 6 to 8 hours.

Examples of long-acting barbiturates are phenobarbital and barbital. Their slow onset of action discourages their abuse.
The intermediate-acting barbiturates have an onset of action of 15 to 30 minutes and a duration of action of 4 to 6 hours.

Examples of intermediate-acting barbiturates are amobarbital, butabarbital, and Tuinal.
The short-acting barbiturates have an onset of action of 10 to 15 minutes and have a duration of action of 2 to 4 hours.

Examples of short-acting barbiturates are secobarbital and pentobarbital.
The ultra-short-acting barbiturates have an onset of action of 0 to 45 seconds and a duration of action 15 minutes to 3 hours. These are barbiturates used as anesthetics. Their effects are generally felt within one minute of intravenous administration.

Examples of ultra short-acting barbiturates are thiopenthal sodium, hexobarbital, and methohexital. The rapid onset and brief duration of action practically precludes the use of ultra-short-acting barbiturates in the street environment.
Concern about the addiction potential of barbiturates and the ever-increasing numbers of fatalities associated with them led to the development of alternative medications.

Barbiturates can be detected in urine drug testing from 2 to 10 days. Depending on usage.

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Employee drug testing has gained significant importance in organizations as it helps to find out drug abuse problems among employees. Maintaining a drug free environment fosters employee productivity, professionalism, and prevents absenteeism, addiction related crime, accidents, and injuries. Conducting pre-employment and random employee drug testing keeps a check on addiction and ensures prevailing of a safe and productive work environment.

Safety at Work Place

The organizations that conduct employee drug testing can ensure that the work environment is free from any form of addiction related crimes, injures, and accidents. Employee drug testing increases the safety at the job and maintains a safe and secure environment. Conducting pre-employment drug testing can prevent addicted persons from joining the organization and spoil the working environment. Random employee drug testing prevents existing employees to abuse to any kind of drug before coming to workplace.

Improves Productivity and Quality of Work

Employee productivity and professional environment is important for any business establishment. Drug abuse is a potential threat to any organization as it hampers the employee productivity and encourages negative traits and unprofessional behavior. Detecting drug abuse among present and future employees will lead to a healthier working environment. A healthier environment will increase the productivity and quality of work thereby increasing the profits of organization. It has been found that doing away with employees prone to addiction significantly improves productivity in organization and reduces accidents.

Reduces Health Costs of Company

The employee drug testing effectively eliminates the drug addicted employees and cleans the system. Thus, getting rid of such employee can save significant amount of money given by company towards health insurance premiums and other health costs. The addicted employees suffer from sudden mood swings and irrational behavior patterns that can result in work place accidents. The company can save health costs towards medical treatment of such employees due to workplace accidents and illnesses that occur due to addiction. Organizations can also save on recruitment costs towards hiring, firing, and training as employee drug testing ensures that present and future employees are drug abuse free.

Helps in Maintaining Integrity and Discipline

Drug free environment in organizations is a nurturing habitat for positive qualities like integrity, discipline, professionalism, productivity etc. Removing addicted employees ensures that there will be less workplace conflicts, unscrupulous behavior at workplaces. Removing addicted employees will also send a message across other employees that company has zero tolerance towards addiction. This helps to ensure that there is harmonious environment where integrity and discipline is maintained.

Employee drug testing can be effectively performed in organizations using saliva testing, urine testing and hair follicle testing. Saliva testing is non-invasive and provides instant results. Urine drug screening is done using test strips and provides accurate and reliable results. The hair follicle testing is non-invasive and performed in laboratories. It plays an important part in employee drug testing as it can give drug abuse history for much longer period of time.

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The method of collecting a urine sample for drug screening can be important. Some illicit drug users may attempt to substitute another person’s urine, or chemically alter their own specimen. If the urine drug screen is being used for an important decision, such as employment or legal action, procedures to minimize chances of an adulterated or substituted sample may be necessary. These include measuring the temperature or pH of the sample immediately after it is procured, and using tamper-proof containers. Supervised specimen collection may be conducted to ensure that the urine indeed comes from the person being screened.

The most commonly used method for urine drug screening is immunoassay, a rapid and accurate test that uses antibodies embedded on test strips to reveal drug use. Antibodies react only in the presence of very specific substances—in this case, drugs present in urine. When a sufficient concentration of a drug (or drugs) are present, the test strip will indicate which substances have been detected. A control band on each strip confirms that the test was done correctly.

Positive screening results should always be confirmed by a more sensitive method. The most widely accepted corroborative test for all drugs is gas chromatography/mass spectrometry (GC/MS), which can determine the specific substances in the body by recognizing not only the molecular structure of the original compound, but also its metabolite, a chemical created when the drug is metabolized.

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Drug testing is now faster, less expensive and more convenient than ever thanks to the availability of on-site rapid Instant Drug Tests kits. No more scheduling fiascos, waiting for up to a week for results and costly fees. The new generation of onsite rapid drug testing kits are fast, easy to use and less expensive than ever.

If you are a manager or small business owner considering a drug testing solution, on-site rapid drug test kits might be the answer you have been waiting for.

• Fast. Results are often available in less than ten minutes instead of waiting hours and even days for laboratory results. On-site rapid drug test kits are almost instantaneous.

Less Expensive. On-site rapid Instant Drug Tests test kits can provide the initial screening results for a positive drug test or drug metabolite confirmations for a fraction of the ordinary lab testing fee.

• Easy to Use. No special equipment, training or knowledge is required to use on-site rapid drug test kits. The kits are packaged in a compact kit that contains everything needed. Results are provided in an easy to see visual display that doesnt require interpretation.
• Accurate. On-site rapid Instant Drug Tests kits report up to 99% accuracy.
• On-site. No need to send employees or job applicants to a special laboratory; now the drug test is where you need it and when you need it. At the office or off-site locations, the convenience of onsite drug testing will revolutionize the way you think about testing.
• Versatile. On-site rapid Instant Drug Tests kits have been designed with real life applications in mind. They are used by law enforcement, Fortune 500 companies, schools, staffing agencies and small business owners of all types in a variety of industries.